Mhlophe umgubo I-300/800 a tu / g I-hirudin powder
1. Intshayelelo ye I-hirudin powder:
I-hirudin powder yeyona nto isebenzayo kwaye ifundwe kakuhle izithako ezisebenzayo ezikhutshiweyo kwi-lees kunye namadlala amava, kwaye yiprotein encinci (iPeptide) equka i-65-66 Amino Acids. I-hirudin inesiphumo esiqinileyo esiyinqanda kwi-rambin kwaye yeyona nto inamandla yendalo enesithambiso enesifo setrolin ifunyenwe ukuza kuthi ga ngoku.
2 . Ulwazi olusisiseko :
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Product Name
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Hirudin
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Specification
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300/800 ATU/G
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Appearance
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White powder
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CAS No.
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113274-56-9
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Molecular formula
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C66H93N13O25
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Molecular weight
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1468.52
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Boiling point
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1913.6±65.0 °C(Predicted)
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Density
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1.384±0.06 g/cm3(Predicted)
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3. Umsebenzi
Iziphumo ze-Anticoulant
hirudin inesiphumo esithile nelisebenza kakuhle kwi-rambin, esinokuthi sithintele ngokuthe ngqo i-thronin kwaye sithintele umsebenzi weprotheyini ye-protein, ke inesiphumo se-anticouhlant. Xa kuthelekiswa ne-heparin, i-Hirudin Dosage incinci, ayizange ibangele ukopha, kwaye ayixhomekeki kwi-gondogenology
Iziphumo ze-anti-roph
Ukuphucula i-microcirccotions kunye nokukhuthaza imetabolism
kunokunciphisa ukuphendula kwe-inframis kunye ne-Edema malunga nokunyuka kwengqondo, ukunciphisa ukunyuka kwengcinezelo, ukuphucula ukusasazwa kwendawo, kunye nokwenza lula ukubuyiselwa kwendawo ye-neurological; Inokukhuthaza ukuthathwa kwe-hematoma yovavanyo endlebeni.
Ukuphuculwa kwe-cholesterol kunye neCologlycercerces
leelech kunefuthe elibonakalayo kwi-cholesterol kunye ne-triglycerides kwi-hyperlifidemia. I-hirudin inesiphumo sokuthintela iiseli ze-tumor kwaye inempembelelo yokukhula komhlaza weSibindi. Ngenxa yesiphumo sayo esiphakamileyo se-anticouhlant, iLeech iququzelele ukungenisa amachiza amachiza kunye neeseli ezisebenzayo ezigwenxa kwizicubu zomhlaza ukuze zibulale iiseli zomhlaza.
I-Anti-MyoCardial Ischemia kunye ne-Dyskinesia yeTyskinesia
i-Ackeed Eastient inesiphumo esibonisa i-achanatistic kwi-ischemia ye-Bychemia kwaye i-NERDETMIA; Inaliti yeLevin Intraperitoneal Inaliti inokunyusa ukuhamba kwegazi kwesondlo. Isisombululo se-hirudin nge-sedation sinokukhuthaza kwaye sinciphise i-fibrillation ye-fibrillation kunye nempendulo ye-phellipres, kwaye iziphumo ezifanayo zifunyenwe kuvavanyo kwi-hematomaus ye-hematomaus.
Iziphumo kwi-Difobetes Mellitus kunye nokunyangwa kwe
-insulin Ukungaxhathisi kuyaxhaphake kwizigulana ezinohlobo lwe-il yeswekile, inika ingxelo phantse ingama-90% okanye ngaphezulu. I-Hirudin inokusebenza njenge-Insulin ye-Insulin, enokuphucula ubuntununtunu bokwahluka komzimba, kwaye yi-insulin yayo enokuvuselela umsebenzi ngokupheleleyo kwaye ihlise iswekile yegazi; Iswekile inokutshabalalisa zonke iindonga zegazi, zivelisa i-infrobmatory kwaye iyenza kwi-pirusisis yamanzi, izintso kunye ne-hirudin inokunciphisa ukuvela kwe-idommatory ye-FOLLY kwaye ithintele i-thrombodin.
4. Isicelo se
-hirudin powder yiklasi ethenjisiweyo ye-anticoursula kunye ne-anti-stasis, enokusetyenziswa kunyango lwezifo ezahlukeneyo ze-romboic, ngakumbi i-vescus quags; Ingasetyenziselwa ukuthintela ukwenziwa kwe-artional thrombolial emva kotyando, ukuthintela ukwenziwa kwe-rubbus emva kokupheliswa kwe-rarib okanye emva kokuhlaziywa; Ukuphucula ukujikeleza okungacacanga kunye nenkqubo ye-hemodialysis. Kwimicrosurgery, ehlala isilele ngenxa ye-vascular emnyama kwi-Anastomosis, ukusetyenziswa kwe-hirudin kunokuphakamisa ukuphiliswa kwenxeba. Uphando lubonakalisile ukuba i-hirudin ingadlala indima kunyango lwethumba. Imisa i-metastasis yeeseli ze-tumor kwaye iqinisekiswe ukusebenza kakuhle kwi-fibrosarcoma, i-osteomarcoma, i-angeliomarcoma, i-melanoma kunye ne-leukemia. I-hirudin inokusetyenziswa ngokudibeneyo kunye ne-chemotherapy kunye nonyango lwe-radiation ukonyusa ukusebenza kakuhle konyango ngenxa yokukhuthaza ukuhamba kwegazi kwi-tuma.
5. Coa
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Product Name
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Freeze-dried powder of Pheasant leech
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Inspection basis
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AJI92
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Batch No.
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SOST20220827
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Quantity
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1000Kg
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Manufacturing Date
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20220827
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Expiry Date
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20240826
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Based on test
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A leech from the 2020 edition of Chinese
Pharmacopoeia
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Sample status
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Powder
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Items
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Unit
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Testing result
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Test method
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Hirudin (antithrombin activity)
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ATU/G
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387.6
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A leech from the 2020 edition of Chinese
Pharmacopoeia
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Iikhathalo zomkhiqizo : Imveliso eshushu yokuthengisa
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