Ukuthengisa okushushu i-picrophylline powder
1. Ukwaziswa kwe -picrophylline powder:
I-bitterophylline powder (i-theachnerne, eyi-1,3,9-titha ye-tetramethylud) yi-Alkaloid ye-purine (i-Femellialoung), i-Femellialoung), eyona nto ixhaphakileyo i-tie amagqabi. Kungenxa yelinye iqela le-methyl kune-caffaine, i-Alkaloids ekrakra inemisebenzi eyahlukileyo yomzimba kunye nemiphumo yempilo evela kwi-caffeine, etsala ingqalelo ebanzi kubaphengululi kwizifundo nakwimimandla yamayeza.
2 . Ulwazi olusisiseko :
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Product Name
|
Picrophylline
|
|
Specification
|
98%
|
|
Appearance
|
White powder
|
|
CAS No.
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2309-49-1
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|
Molecular formula
|
C9H12N4O3
|
|
Molecular weight
|
224.22
|
|
EINECS No.
|
218-994-1
|
|
Melting point
|
226°C
|
|
Boiling point
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365.61°C (rough estimate)
|
|
Density
|
1.3055 (rough estimate)
|
3. Umsebenzi
1.Ubhaptili unokusetyenziselwa ukukhulisa amanqanaba eDopamine;
2.Uncwadi ngesibhaliweyo unokusetyenziselwa ukunciphisa uxinzelelo kunye noxinzelelo;
3.Ubhaptili unokusetyenziselwa ukunciphisa ukuvuvukala kuwo wonke umzimba;
I-Screearine inokusetyenziselwa ukwenza i-thermogenesis kwaye ilungiselele ukutsha kwamafutha.
4. Isicelo
I-Pipuraline sisiyobisi se-methyl pururine. Ineziphumo zentliziyo yentliziyo, i-thoretic, i-dilary yomsebenzi, ukuphumla i-brothocial rocle kunye nokukhuthaza inkqubo ye-nevaring ephambili. Isetyenziselwa ikakhulu unyango lwe-asthma, i-Emfysema, i-bronchitis, kunye ne-Cardiac Dyspnea.
I-5. Coa
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Test items
|
Test standard
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Test result
|
Test method
|
|
Character
|
A white to almost white crystalline powder
|
White crystalline powder
|
ZSQB12-2
|
|
HPLC
|
≥99%
|
99.9%
|
HPLC
|
|
Loss on dry
|
<1.0%
|
0.6%
|
USP41
|
|
Related substance
|
Isolate impurity ＜0.2%, total impurities＜1.0%
|
Conform
|
HPLC
|
|
Heavy metal
|
<10ppm
|
Conform
|
USP41
|
|
Pb
|
≤0.5ppm
|
＜0.5 ppm
|
USP41
|
|
Cd
|
≤0.5ppm
|
＜0.5 ppm
|
USP41
|
|
As
|
≤0.5ppm
|
＜0.5 ppm
|
USP41
|
|
Hg
|
≤0.1ppm
|
＜0.1 ppm
|
USP41
|
|
Residue on ignition
|
≤0.5%
|
0.1%
|
USP41
|
|
Ash content
|
≤ 0.5％
|
0.1%
|
USP41
|
|
Melting point
|
227-232 ℃
|
229.5-231℃
|
USP41
|
|
Total Plate Count
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≤1000cfu/g
|
≤10cfu/g
|
USP41<2021>/<2022>
|
|
Total Yeast&Mold
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≤100cfu/g
|
Negative
|
USP41<2021>/<2022>
|
|
S. aureus
|
Negative
|
Negative
|
USP41<2021>/<2022>
|
|
Salmonrlla
|
Negative
|
Negative
|
USP41<2021>/<2022>
|
|
E.Coli
|
Negative
|
Negative
|
USP41<2021>/<2022>
|
|
Bulk Density
|
≥0.55g/ml
|
0.6g/ml
|
USP41
|
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